Christine Kottaridi, Biologist, MSc, PhD

Aris Spathis, Biologist, PhD

Evangelia Aga, Biologist

Chara Dova, Biologist

Examinations – Techniques

  • Detection and typing of 35 Human PapillomaVirus (HPV) subtypes by low density DNA microarray technique
  • Detection and typing of 37 HPV subtypes by PCR and hybridization in labeled probe specific strips
  • Detection and typing E6/E7 mRNA of strains HPV16, HPV18, HPV31, HPV33 and HPV45 with NASBA technique
  • Detection of cells rate overexpressing E6/E7 mRNA of HPV virus by flow cytometry
  • Detection and typing of 17 respiratory viruses and HHV viruses by DNA low density microarray technique
  • Detection of pathogens (CMV, PCP, MTB, Chlamydia trachomatis, Legionella pneumoniae, etc.) on cytologic materialvia Real-time PCR
  • Detection of mutations for genes KRAS, EGFR, BRAF with Real-time PCR technique for therapy determination in patients with colorectal cancer, non-small cell lung cancer and melanoma
  • Detection of of T and B lymphocytes clonality via PCR technique
  • Detection of promoter methylation for genes associated with cell cycle and DNA repair enzymes

 Research Activities

  • Prevalence of HPV infection and HPV types distribution in the population, cytological and histological relations
  • Association of HPV infection with cell cycle parameters and epigenetic phenomena
  • Phylogenetic analysis of strains HPV16, HPV18, HPV31, HPV33 and HPV45
  • Analysis of molecular parameters for colon carcinomas and association with targeted chemotherapy
  • Detection of the most frequent rotavirus found in gastrointestinal infections via Real-time PCR
  • Epidemiology of gene alterations and relation with the success of targeted therapy
  • Epidemiology of respiratory system viral infections